Hepatitis C virus (HCV) infects the liver. Chronic infection with HCV
causes inflammation in this vital organ and slowly degrades it as
healthy tissue is replaced with scar tissue. This ongoing injury to the
liver results in complications, including bacterial infections, internal
bleeding and liver, kidney and brain dysfunction. If left untreated,
HCV infection can cause severe liver injury, the liver can stop working
and death can occur. HCV infection also increases the risk for
developing liver cancer.
Impact of HIV co-infection
Co-infection with HCV and HIV is relatively common, as both viruses
have shared routes of infection. HIV-HCV co-infection accelerates the
pace of HCV-related liver injury.
Historically, co-infected people have had increased rates of illness
and death compared to people with HCV infection alone (mono-infection).
There are at least two reasons for this, as follows:
Labels: Canada, Clinical Trials, co-infection