The Prevalence of Cirrhosis in Patients with Hepatitis C Is Growing | Caitlyn Fitzpatrick

Patients with chronic hepatitis C can develop cirrhosis, a serious condition characterized by scarring of the liver – but just how many patients actually reach this point? 

There’s been an increase in the number of Americans with hepatitis C who also have cirrhosis, according to a study published in the Journal of Hepatology. This prevalence was analyzed both in people who knew that they had the liver infection and those who were unaware. 

The researchers pulled data from the National Health and Nutrition Examination Survey (NHANES) consisting of 52,644 participants at least 21 years of age. The majority of them were tested for hepatitis C and 725 individuals were diagnosed. Advanced fibrosis was considered greater than 3.25 using Fib-4 and advanced cirrhosis was considered greater than 2.0 using AST to Platelet Ratio Index (APRI). Based on those numbers, the patients were split into groups – Era 1 (1988 – 1994), Era 2 (1999 – 2006), and Era 3 (2007 – 2012). 

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